Consensus Diagnosis and Predictors of Diagnostic Accuracy in the National
Alzheimer's Disease Centers 
 
   Lead Investigator:    Kate Bristow
   Institution      :    NACC
   E-Mail           :    kbristow@uw.edu
   Proposal ID      :    220


   Publications:


1  Bristow KE, Besser LM, Monsell SE, Brenowitz W, Hawes SE, Kukull WA
   Consensus Diagnosis and Predictors of Diagnostic Accuracy in the National Alzheimer's Disease Centers
   Abstract  Alzheimers Dement,9:P321,2013,

   PUBLISHED





   Proposal Description:
   (1) To determine the degree to which the following factors predict non-agreement between clinical diagnosis and neuropathologic features of AD: (a) diagnostic method: single clinician v. consensus panel (b) presence of non-neurodegenerative disease: depression, substance abuse, history of traumatic brain injury (c) informant characteristics: presence, relationship and reliability (d) time: years since onset of cognitive decline, years to death since last visit, years on study at ADC.   (2) To explore the extent to which any identified factors predict the misdiagnosis of one disease as another.